1) depressed mood most of the day, nearly every day as indicated by either subjective report (e.g., feels sad or empty) or observation made by others (e.g. appears tearful) Note: In children and adolescents can be irritable mood.
2) Markedly diminished interest or pleasure in all or almost all activities most of the day, nearly every day (as indicated by either subjective account or observation made by others)
3) Significant weight loss when not dieting or weight gains (e.g. a change of more than 5% of body weight in a month) or decrease or increase in appetite nearly every day. Note: In children consider failure to make expected weight gains.
4) Insomnia or hypersomnia nearly every day.
5) Psychomotor agitation or retardation nearly every day (observable by others not merely subjective feelings of restlessness or being slowed down)
6) Fatigue or loss of energy nearly every day
7) Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional)nearly every day (not merely self-reproach or guilt about sick)
8) Diminished ability to think or concentrate or indecisiveness nearly every day(either by subjective account or as observed by others)
9) Recurrent thought of death (not just fear of dying) recurrent suicidal indentation without a specific plan or a suicide attempt for committing suicide







